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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL4536732
Molecular formula	C23H24N2O3S
IUPAC name	6-(2,6-dimethoxyphenyl)-1-[[3-(1,3-thiazol-5-yl)phenyl]methyl]piperidin-2-one
Molecular weight	408.516
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.8
Synonyms	US9242970, 42 ACRPTJULOPXGFI-UHFFFAOYSA-N CHEMBL3962071 BDBM202899 6-(2,6-dimethoxyphenyl)-1-(3-(thiazol-5-yl)benzyl)piperidin-2-one
Inchi Key	ACRPTJULOPXGFI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24N2O3S/c1-27-19-9-5-10-20(28-2)23(19)18-8-4-11-22(26)25(18)14-16-6-3-7-17(12-16)21-13-24-15-29-21/h3,5-7,9-10,12-13,15,18H,4,8,11,14H2,1-2H3
PubChem CID	69082749
ChEMBL	CHEMBL3962071
IUPHAR	N/A
BindingDB	202899
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
535961	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
535962	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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