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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	6-bromo-N-[(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl]-2-(4-methylphenyl)quinoline-4-carboxamide
Molecular formula	C24H23BrN4O
IUPAC name	6-bromo-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-2-(4-methylphenyl)quinoline-4-carboxamide
Molecular weight	463.379
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.7
Synonyms	AC1N7IAP NCGC00101043-01 CHEMBL1515178 ZINC2503257 MCULE-6306305958 AKOS001692218 ST50937891 EU-0016721 [6-bromo-2-(4-methylphenyl)(4-quinolyl)]-N-[(1-ethyl-3-methylpyrazol-4-yl)meth yl]carboxamide 6-bromo-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-2-(4-methylphenyl)quinoline-4-carboxamide MolPort-001-535-189 STK422347 HMS1803C10 [ Show all ]
Inchi Key	ACKGZGJBVZHGFY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H23BrN4O/c1-4-29-14-18(16(3)28-29)13-26-24(30)21-12-23(17-7-5-15(2)6-8-17)27-22-10-9-19(25)11-20(21)22/h5-12,14H,4,13H2,1-3H3,(H,26,30)
PubChem CID	4302940
ChEMBL	CHEMBL1515178
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1659	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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