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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL21939
Molecular formula	C35H35N3O2
IUPAC name	1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-[5-methyl-2-(4-phenylphenyl)-1H-indol-3-yl]propan-1-one
Molecular weight	529.684
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	7.0
Synonyms	BDBM50099553 SCHEMBL6928161 1-[4-(2-Methoxyphenyl)piperazino]-3-[2-(4-biphenylyl)-5-methyl-1H-indole-3-yl]-1-propanone 3-(2-Biphenyl-4-yl-5-methyl-1H-indol-3-yl)-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one ACJFETYSCBTCMR-UHFFFAOYSA-N 4-(2-Methoxyphenyl)-1-{3-[5-methyl-2-(4-phenylphenyl)-1H-indol-3-yl]-1-oxopropyl}piperazine [ Show all ]
Inchi Key	ACJFETYSCBTCMR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H35N3O2/c1-25-12-18-31-30(24-25)29(35(36-31)28-15-13-27(14-16-28)26-8-4-3-5-9-26)17-19-34(39)38-22-20-37(21-23-38)32-10-6-7-11-33(32)40-2/h3-16,18,24,36H,17,19-23H2,1-2H3
PubChem CID	18669085
ChEMBL	CHEMBL21939
IUPHAR	N/A
BindingDB	50099553
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1623	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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