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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LORZK
Molecular formula	C17H19FN2OS
IUPAC name	(5-ethylthiophen-2-yl)-[4-(4-fluorophenyl)piperazin-1-yl]methanone
Molecular weight	318.41
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.9
Synonyms	1-[(5-ethyl-2-thienyl)carbonyl]-4-(4-fluorophenyl)piperazine MLS000065786 ZINC1054496 AKOS003352555 SMR000080471 (5-ethylthiophen-2-yl)-[4-(4-fluorophenyl)piperazin-1-yl]methanone HMS2446O15 ST50858062 5-ethyl(2-thienyl) 4-(4-fluorophenyl)piperazinyl ketone MolPort-001-613-985 SR-01000291799 (5-ethylthiophen-2-yl)[4-(4-fluorophenyl)piperazin-1-yl]methanone MCULE-6572330991 STK463466 REGID_for_CID_1245963 CHEMBL1605370 SR-01000291799-1 [ Show all ]
Inchi Key	ABSCDJBZRCWAFR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19FN2OS/c1-2-15-7-8-16(22-15)17(21)20-11-9-19(10-12-20)14-5-3-13(18)4-6-14/h3-8H,2,9-12H2,1H3
PubChem CID	1245963
ChEMBL	CHEMBL1605370
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1119	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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