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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL469343
Molecular formula	C27H25ClN4OS
IUPAC name	2-(4-chlorophenyl)-5-[1-methyl-3-(2-pyrrolidin-1-ylethyl)indol-6-yl]-[1,3]thiazolo[5,4-c]pyridin-4-one
Molecular weight	489.034
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.6
Synonyms	BDBM50278501 2-(4-chlorophenyl)-5-(1-methyl-3-(2-(pyrrolidin-1-yl)ethyl)-1H-indol-6-yl)thiazolo[5,4-c]pyridin-4(5H)-one
Inchi Key	AAMWNCYHHIFEER-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H25ClN4OS/c1-30-17-19(10-14-31-12-2-3-13-31)22-9-8-21(16-24(22)30)32-15-11-23-25(27(32)33)34-26(29-23)18-4-6-20(28)7-5-18/h4-9,11,15-17H,2-3,10,12-14H2,1H3
PubChem CID	44592169
ChEMBL	CHEMBL469343
IUPHAR	N/A
BindingDB	50278501
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
349	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422

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