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Name | 5-hydroxytryptamine receptor 2C |
---|---|
Species | Canis lupus familiaris (Dog) |
Gene | HTR2C |
Synonym | 5-HT-2C 5-HT2C 5-HTR2C Serotonin receptor 2C |
Disease | N/A for non-human GPCRs |
Length | 458 |
Amino acid sequence | MVNLRKAVHSFLVHLIGLLVWQCDISVSPVAALVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPVEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHVLRRQALMLLHGHVEEPPRINLDFLKCCRRNGTEEENSANPNQDSNPRRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLVMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKPEKKPPVRQMPRVAATALSGRELNVNIYRHTNEPVLKKANDKEPGIEMQVENLELPVNPSSVVSERISSV |
UniProt | Q60F97 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1770041 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
54735 | 2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine | C15H17N3 | 239.322 | 3 / 1 | 2.1 | Yes |
83888 | Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
334993 | (S)-mianserin | C18H20N2 | 264.372 | 2 / 0 | 3.4 | Yes |
400713 | Lorcaserin | C11H14ClN | 195.69 | 1 / 1 | 2.7 | Yes |
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