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Name | B1 bradykinin receptor |
---|---|
Species | Oryctolagus cuniculus (Rabbit) |
Gene | BDKRB1 |
Synonym | B1R BK-1 receptor |
Disease | N/A for non-human GPCRs |
Length | 352 |
Amino acid sequence | MASQGPLELQPSNQSQLAPPNATSCSGAPDAWDLLHRLLPTFIIAIFTLGLLGNSFVLSVFLLARRRLSVAEIYLANLAASDLVFVLGLPFWAENVRNQFDWPFGAALCRIVNGVIKANLFISIFLVVAISQDRYSVLVHPMASRRGRRRRQAQATCALIWLAGGLLSTPTFVLRSVRAVPELNVSACILLLPHEAWHWLRMVELNLLGFLLPLAAILFFNCHILASLRRRGERVPSRCGGPRDSKSTALILTLVASFLVCWAPYHFFAFLECLWQVHAIGGCFWEEFTDLGLQLSNFSAFVNSCLNPVIYVFVGRLFRTKVWELCQQCSPRSLAPVSSSRRKEMLWGFWRN |
UniProt | P48748 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4087 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
8355 | CHEMBL221998 | C24H20Cl2N4O3 | 483.349 | 6 / 2 | 5.4 | No |
9246 | Safotibant | C25H34N4O5S | 502.63 | 7 / 1 | 1.6 | No |
15061 | CHEMBL507168 | C26H32Cl2N2O5S | 555.511 | 6 / 3 | 4.0 | No |
19230 | CHEMBL1934259 | C32H32N2O3 | 492.619 | 4 / 1 | 5.4 | No |
27060 | CHEMBL1834749 | C31H33N5O2 | 507.638 | 5 / 1 | 4.3 | No |
57723 | CHEMBL1834616 | C32H33ClN4O2 | 541.092 | 4 / 1 | 5.6 | No |
61145 | CHEMBL1835756 | C32H32N2O3 | 492.619 | 4 / 1 | 5.4 | No |
65170 | CHEMBL227870 | C29H31F4N3O5S | 609.637 | 11 / 3 | 3.5 | No |
67250 | CHEMBL227713 | C31H33F4N3O4S | 619.676 | 10 / 2 | 5.0 | No |
70028 | CHEMBL1835762 | C32H34N4O2 | 506.65 | 4 / 1 | 5.0 | No |
70458 | CHEMBL1934256 | C32H31FN2O3 | 510.609 | 5 / 1 | 5.5 | No |
127116 | CHEMBL189123 | C27H25Cl2N5O4S | 586.488 | 6 / 3 | 3.1 | No |
139507 | chroman 28 | C34H37N3O4S | 583.747 | 6 / 2 | 5.2 | No |
158032 | CHEMBL1934258 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
174239 | CHEMBL1777958 | C29H38N4O4S | 538.707 | 6 / 2 | 2.8 | No |
184779 | CHEMBL221984 | C24H20ClFN8O | 490.927 | 8 / 2 | 4.3 | Yes |
214645 | CHEMBL225607 | C24H20ClFN4O3 | 466.897 | 7 / 2 | 4.9 | Yes |
218136 | CHEMBL1834619 | C31H32ClN5O2 | 542.08 | 5 / 1 | 4.9 | No |
228401 | CHEMBL1934253 | C32H34N4O2 | 506.65 | 4 / 1 | 5.0 | No |
228920 | CHEMBL488501 | C26H32Cl2N2O5S | 555.511 | 6 / 3 | 4.0 | No |
229764 | CHEMBL1834750 | C31H31ClN4O3 | 543.064 | 5 / 1 | 5.0 | No |
244809 | CHEMBL387638 | C24H20ClFN8O | 490.927 | 8 / 2 | 4.9 | Yes |
262576 | CHEMBL1934261 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
267433 | CHEMBL508632 | C26H33ClN2O5S | 521.069 | 6 / 3 | 3.4 | No |
300977 | CHEMBL1834751 | C31H31F2N5O2 | 543.619 | 7 / 1 | 4.5 | No |
305883 | CHEMBL402831 | C20H16ClF5N4O3 | 490.815 | 11 / 2 | 3.8 | No |
306999 | CHEMBL227600 | C30H31F4N3O4S | 605.649 | 10 / 2 | 4.6 | No |
307660 | CHEMBL1934262 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
310878 | CHEMBL222038 | C25H20ClFN6O2 | 490.923 | 8 / 2 | 5.3 | No |
313782 | CHEMBL1934257 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
361543 | CHEMBL1934265 | C33H34N2O3 | 506.646 | 4 / 1 | 5.8 | No |
362342 | CHEMBL1834620 | C31H32ClN5O2 | 542.08 | 5 / 1 | 4.9 | No |
373348 | CHEMBL1934254 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
374948 | CHEMBL1934263 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
386706 | MK-0686 | C22H19ClF4N2O4 | 486.848 | 8 / 2 | 4.5 | Yes |
389812 | CHEMBL453339 | C30H36N2O5S | 536.687 | 6 / 3 | 4.0 | No |
396923 | CHEMBL1934255 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
399183 | CHEMBL1834752 | C31H32FN5O2 | 525.628 | 6 / 1 | 4.4 | No |
404205 | CHEMBL359553 | C31H29N5O4S | 567.664 | 6 / 3 | 3.1 | No |
421231 | CHEMBL486456 | C30H42N2O5S | 542.735 | 6 / 3 | 4.4 | No |
427766 | CHEMBL1934264 | C32H31FN2O3 | 510.609 | 5 / 1 | 5.5 | No |
428853 | CHEMBL455642 | C27H33F3N2O5S | 554.625 | 9 / 3 | 3.6 | No |
429281 | CHEMBL1934260 | C32H31ClN2O3 | 527.061 | 4 / 1 | 6.0 | No |
435714 | CHEMBL455643 | C27H33F3N2O5S | 554.625 | 9 / 3 | 3.6 | No |
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