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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	N-arachidonyl glycine receptor
Species	Homo sapiens (Human)
Gene	GPR18
Synonym	GPCRW G-protein coupled receptor 18 N-arachidonoyol glycine receptor NAGly receptor GPR18
Disease	N/A
Length	331
Amino acid sequence	MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
UniProt	Q14330
Protein Data Bank	N/A
GPCR-HGmod model	Q14330
3D structure model	This predicted structure model is from GPCR-EXP Q14330.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2384898
IUPHAR	89
DrugBank	BE0002304

Ligand

Name	CHEMBL2181541
Molecular formula	C28H36O4
IUPAC name	5-methoxy-3-[(2-methoxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one
Molecular weight	436.592
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	8.7
Synonyms	BDBM50398219
Inchi Key	GLBHDBKJJWTLPC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H36O4/c1-6-7-8-9-12-15-28(2,3)22-18-25(31-5)23-17-21(27(29)32-26(23)19-22)16-20-13-10-11-14-24(20)30-4/h10-11,13-14,17-19H,6-9,12,15-16H2,1-5H3
PubChem CID	70678100
ChEMBL	CHEMBL2181541
IUPHAR	N/A
BindingDB	50398219
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	33.0 %	PMID23679955	ChEMBL
IC50	<10000.0 nM	PMID23679955	BindingDB,ChEMBL

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