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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Mu-type opioid receptor
Species	Rattus norvegicus (Rat)
Gene	Oprm1
Synonym	Opioid receptor B opioid receptor OP3 mu receptor MOR-1 MOPr MOP M-OR-1 opioid receptor, mu 1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	398
Amino acid sequence	MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
UniProt	P33535
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL270
IUPHAR	319
DrugBank	N/A

Ligand

Name	CHEMBL161512
Molecular formula	C18H22N2O2
IUPAC name	N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide
Molecular weight	298.386
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.1
Synonyms	BDBM50017418 Furan-2-carboxylic acid (1-phenethyl-piperidin-4-yl)-amide SCHEMBL17512173
Inchi Key	ANKJEEDQRYNCTR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22N2O2/c21-18(17-7-4-14-22-17)19-16-9-12-20(13-10-16)11-8-15-5-2-1-3-6-15/h1-7,14,16H,8-13H2,(H,19,21)
PubChem CID	35121669
ChEMBL	CHEMBL161512
IUPHAR	N/A
BindingDB	50017418
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<100.0 nM	PMID2563773	BindingDB,ChEMBL

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