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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Mus musculus (Mouse)
Gene	Drd2
Synonym	D2 receptor D2(415) and D₂₍₄₄₄₎ D2A and D_2B D2R dopamine D2 receptor dopamine receptor 2 [ Show all ]
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
UniProt	P61168
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3427
IUPHAR	215
DrugBank	N/A

Ligand

Name	CHEMBL47482
Molecular formula	C15H15N
IUPAC name	9,10-dihydroanthracen-9-ylmethanamine
Molecular weight	209.292
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	2.7
Synonyms	9-Aminomethyl-9,10-dihydroanthracene PDSP1_001230 (9,10-dihydroanthracen-9-ylmethyl)amine C-(9,10-Dihydro-anthracen-9-yl)-methylamine ZINC13473096 9,10-dihydroanthracene(DHA), 1a D01CXD AMDA PDSP2_001214 22136-76-1 9-(aminomethyl)-9,10-dihydroanthracene DTXSID80439253 BDBM35920 SCHEMBL7003538 [ Show all ]
Inchi Key	GEICAQNIOJFRQN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H15N/c16-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)15/h1-8,15H,9-10,16H2
PubChem CID	10398175
ChEMBL	CHEMBL47482
IUPHAR	N/A
BindingDB	35920
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID11266163	BindingDB,ChEMBL

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