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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 2
Species	Homo sapiens (Human)
Gene	LPAR2
Synonym	endothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4 LPA receptor 2 LPA-2 Edg4 Lysophosphatidic acid receptor Edg-4 Pbx4 pre-B-cell leukemia transcription factor 4 LPA2 receptor [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
UniProt	Q9HBW0
Protein Data Bank	N/A
GPCR-HGmod model	Q9HBW0
3D structure model	This predicted structure model is from GPCR-EXP Q9HBW0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3724
IUPHAR	273
DrugBank	N/A

Ligand

Name	CHEMBL117007
Molecular formula	C19H34NO4P
IUPAC name	3-[[4-(1-hydroxynonyl)phenyl]methylamino]propylphosphonic acid
Molecular weight	371.458
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	0.6
Synonyms	BDBM50148415 SCHEMBL14195651 {3-[4-(1-Hydroxy-nonyl)-benzylamino]-propyl}-phosphonic acid
Inchi Key	AMJOZICHTKJDOI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H34NO4P/c1-2-3-4-5-6-7-9-19(21)18-12-10-17(11-13-18)16-20-14-8-15-25(22,23)24/h10-13,19-21H,2-9,14-16H2,1H3,(H2,22,23,24)
PubChem CID	10287091
ChEMBL	CHEMBL117007
IUPHAR	N/A
BindingDB	50148415
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2100.0 nM	PMID15177461	BindingDB,ChEMBL

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