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GPCR

NamePlatelet-activating factor receptor
SpeciesCavia porcellus (Guinea pig)
GenePTAFR
SynonymPAF-R
PAFr
DiseaseN/A for non-human GPCRs
Length342
Amino acid sequenceMELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProtP21556
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5136
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL127464
Molecular formulaC33H53NO7S2
IUPAC name4-methylbenzenesulfonate;(2-tridecyl-1,3-dioxolan-4-yl)methyl 6-(1,3-thiazol-3-ium-3-yl)hexanoate
Molecular weight639.907
Hydrogen bond acceptor8
Hydrogen bond donor0
XlogPNone
SynonymsN/A
Inchi KeyFTVIPJXIRMFEKK-UHFFFAOYSA-M
Inchi IDInChI=1S/C26H46NO4S.C7H8O3S/c1-2-3-4-5-6-7-8-9-10-11-14-17-26-30-22-24(31-26)21-29-25(28)16-13-12-15-18-27-19-20-32-23-27;1-6-2-4-7(5-3-6)11(8,9)10/h19-20,23-24,26H,2-18,21-22H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
PubChem CID14785917
ChEMBLCHEMBL127464
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
Partition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
IC5020000.0 nMPMID1992139ChEMBL

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