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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide Y receptor type 5
Species	Homo sapiens (Human)
Gene	NPY5R
Synonym	NPYY5-R NPY5-R NPY-Y5 receptor neuropeptide Y receptor type 5 food intake receptor Y5 receptor [ Show all ]
Disease	Eating disorder; Obesity Eating disorder; Obesity; Diabetes Major depressive disorder Obesity
Length	445
Amino acid sequence	MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
UniProt	Q15761
Protein Data Bank	N/A
GPCR-HGmod model	Q15761
3D structure model	This predicted structure model is from GPCR-EXP Q15761.
BioLiP	N/A
Therapeutic Target Database	T20331
ChEMBL	CHEMBL4561
IUPHAR	308
DrugBank	N/A

Ligand

Name	CHEMBL1081469
Molecular formula	C18H18N4S2
IUPAC name	N-[2-[4-(4,5-dihydro-1,3-thiazol-2-ylamino)phenyl]ethyl]-1,3-benzothiazol-2-amine
Molecular weight	354.49
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.5
Synonyms	N-(4-(4,5-dihydrothiazol-2-ylamino)phenethyl)benzo[d]thiazol-2-amine SCHEMBL14000703 BDBM50312007
Inchi Key	FTGKJTDOICYFTN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H18N4S2/c1-2-4-16-15(3-1)22-18(24-16)19-10-9-13-5-7-14(8-6-13)21-17-20-11-12-23-17/h1-8H,9-12H2,(H,19,22)(H,20,21)
PubChem CID	46880224
ChEMBL	CHEMBL1081469
IUPHAR	N/A
BindingDB	50312007
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID19864135	BindingDB,ChEMBL

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