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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	Cholecystokinin receptor type A
Species	Rattus norvegicus (Rat)
Gene	Cckar
Synonym	CCK-A receptor CCK-AR CCK1 receptor CCK1-R cholecystokinin receptor type A cholecystokinin-1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	444
Amino acid sequence	MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
UniProt	P30551
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2871
IUPHAR	76
DrugBank	N/A

Ligand

Name	CHEMBL59859
Molecular formula	C29H34N2O3
IUPAC name	2-adamantyl N-[2-(2-phenylethylcarbamoyl)-1,3-dihydroinden-2-yl]carbamate
Molecular weight	458.602
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.5
Synonyms	BDBM50289885 (2-Phenethylcarbamoyl-indan-2-yl)-carbamic acid adamantan-2-yl ester
Inchi Key	FONKERDJIZSXKE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H34N2O3/c32-27(30-11-10-19-6-2-1-3-7-19)29(17-22-8-4-5-9-23(22)18-29)31-28(33)34-26-24-13-20-12-21(15-24)16-25(26)14-20/h1-9,20-21,24-26H,10-18H2,(H,30,32)(H,31,33)
PubChem CID	44303651
ChEMBL	CHEMBL59859
IUPHAR	N/A
BindingDB	50289885
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	22.0 %	Bioorg. Med. Chem. Lett., (1997) 7:15:2009	ChEMBL

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