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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Alpha-2A adrenergic receptor
Species	Bos taurus (Bovine)
Gene	ADRA2A
Synonym	Alpha-2A adrenoceptor Alpha-2A adrenoreceptor Alpha-2AAR Alpha-2D adrenergic receptor
Disease	N/A for non-human GPCRs
Length	452
Amino acid sequence	MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSGQPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATAAELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSSEHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
UniProt	Q28838
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4744
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL156283
Molecular formula	C10H15N3
IUPAC name	1,4,5,7,8,9,10,10a-octahydropyrazolo[3,4-a]quinolizine
Molecular weight	177.251
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.0
Synonyms	112114-04-2 BDBM50018734 Pyrazolo[3,4-a]quinolizine, 1,4,5,7,8,9,10,10a-octahydro- 1,4,5,7,8,9,10,10a-Octahydro-pyrazolo[3,4-a]quinolizine AKOS030261762
Inchi Key	FIWQPBGSTABWLI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H15N3/c1-2-5-13-6-4-8-7-11-12-10(8)9(13)3-1/h7,9H,1-6H2,(H,11,12)
PubChem CID	14004033
ChEMBL	CHEMBL156283
IUPHAR	N/A
BindingDB	50018734
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	9549.93 nM	PMID2831365	ChEMBL
Ki	9550.0 nM	PMID2831365	BindingDB
Ki	9600.0 nM	PMID2831365	BindingDB,ChEMBL

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