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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1997793
Molecular formula	C24H22N2O5S
IUPAC name	4-(4-ethoxyphenoxy)-5-methylsulfonyl-2-(naphthalen-1-ylmethyl)pyridazin-3-one
Molecular weight	450.509
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.7
Synonyms	SR-02000001222 SR-02000001222-1
Inchi Key	FHKKBMRSYQABSU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22N2O5S/c1-3-30-19-11-13-20(14-12-19)31-23-22(32(2,28)29)15-25-26(24(23)27)16-18-9-6-8-17-7-4-5-10-21(17)18/h4-15H,3,16H2,1-2H3
PubChem CID	53230266
ChEMBL	CHEMBL1997793
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2550.0 nM	PubChem BioAssay data set	ChEMBL

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