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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melatonin receptor type 1C
Species	Xenopus laevis (African clawed frog)
Gene	mtnr1c
Synonym	Mel-1C-R Mel1c (alpha) receptor Mel1c receptor
Disease	N/A for non-human GPCRs
Length	420
Amino acid sequence	MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR
UniProt	P49219
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5495
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL244472
Molecular formula	C18H24N2O
IUPAC name	N-[3-(1-azatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraen-3-yl)propyl]butanamide
Molecular weight	284.403
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	3.1
Synonyms	BDBM50423059
Inchi Key	FGNIHHCCXIPQRY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H24N2O/c1-2-6-17(21)19-11-4-8-15-13-20-12-5-9-14-7-3-10-16(15)18(14)20/h3,7,10,13H,2,4-6,8-9,11-12H2,1H3,(H,19,21)
PubChem CID	16743295
ChEMBL	CHEMBL244472
IUPHAR	N/A
BindingDB	50423059
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1412.54 nM	PMID17346859	ChEMBL
IC50	1413.0 nM	PMID17346859	BindingDB

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