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Name | Melatonin receptor type 1C |
---|---|
Species | Xenopus laevis (African clawed frog) |
Gene | mtnr1c |
Synonym | Mel-1C-R Mel1c (alpha) receptor Mel1c receptor |
Disease | N/A for non-human GPCRs |
Length | 420 |
Amino acid sequence | MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR |
UniProt | P49219 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5495 |
IUPHAR | N/A |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
16482 | CHEMBL244471 | C17H20N2O | 268.36 | 1 / 1 | 2.4 | Yes |
555577 | 5-MeOT-N-pentanyl | C19H27N3O2 | 329.444 | 2 / 3 | 2.6 | Yes |
40095 | CHEMBL233516 | C16H22N2O2 | 274.364 | 2 / 1 | 2.4 | Yes |
51776 | CHEMBL233517 | C20H22N2O2 | 322.408 | 2 / 2 | 3.7 | Yes |
55349 | CHEMBL244957 | C16H20N2O | 256.349 | 1 / 1 | 2.4 | Yes |
67089 | Melatonin | C13H16N2O2 | 232.283 | 2 / 2 | 0.8 | Yes |
77929 | CHEMBL244472 | C18H24N2O | 284.403 | 1 / 1 | 3.1 | Yes |
86095 | CHEMBL394408 | C21H24N2O2 | 336.435 | 2 / 2 | 4.0 | Yes |
104555 | 7-bromomelatonin | C13H15BrN2O2 | 311.179 | 2 / 2 | 2.3 | Yes |
555904 | DH 97 | C22H26N2O | 334.463 | 1 / 2 | 4.9 | Yes |
124988 | CHEMBL233309 | C14H17BrN2O2 | 325.206 | 2 / 1 | 2.2 | Yes |
139664 | CHEMBL243003 | C22H30N2O | 338.495 | 1 / 1 | 4.6 | Yes |
165860 | CHEMBL233308 | C15H19BrN2O2 | 339.233 | 2 / 2 | 3.1 | Yes |
173230 | CHEMBL391350 | C16H22N2O2 | 274.364 | 2 / 2 | 2.8 | Yes |
180487 | CHEMBL396991 | C17H22N2O | 270.376 | 1 / 1 | 2.8 | Yes |
556208 | Luzindole,N-butanoyl | C21H24N2O | 320.436 | 1 / 2 | 4.4 | Yes |
186836 | CHEMBL242573 | C18H22N2O | 282.387 | 1 / 1 | 2.7 | Yes |
556304 | 5-MeOT-N-propionyl | C17H23N3O2 | 301.39 | 2 / 3 | 1.7 | Yes |
227807 | CHEMBL395221 | C15H20N2O2 | 260.337 | 2 / 2 | 2.4 | Yes |
556423 | N-0889 | C20H22N2O | 306.409 | 1 / 2 | 4.1 | Yes |
556442 | 5-MeOT-N-butanyl | C18H25N3O2 | 315.417 | 2 / 3 | 2.0 | Yes |
279317 | CHEMBL242786 | C19H24N2O | 296.414 | 1 / 1 | 3.3 | Yes |
286060 | CHEMBL396501 | C17H22N2O | 270.376 | 1 / 1 | 2.7 | Yes |
287214 | CHEMBL392421 | C15H20N2O2 | 260.337 | 2 / 1 | 1.9 | Yes |
556606 | Luzindole,N-hexanoyl | C23H28N2O | 348.49 | 1 / 2 | 5.5 | No |
297450 | CHEMBL392422 | C17H24N2O2 | 288.391 | 2 / 1 | 2.7 | Yes |
303513 | CHEMBL242806 | C15H18N2O | 242.322 | 1 / 1 | 1.9 | Yes |
556693 | Luzindole,5-MeOT-N-hexanyl | C24H30N2O2 | 378.516 | 2 / 2 | 5.5 | No |
319020 | CHEMBL233740 | C20H22N2O2 | 322.408 | 2 / 1 | 3.2 | Yes |
328296 | CHEMBL233729 | C14H17BrN2O2 | 325.206 | 2 / 2 | 2.8 | Yes |
337422 | CHEMBL231872 | C14H18N2O2 | 246.31 | 2 / 2 | 2.0 | Yes |
374541 | CHEMBL244263 | C17H22N2O | 270.376 | 1 / 1 | 2.7 | Yes |
557051 | 5-MeOT-N-hexanyl | C20H29N3O2 | 343.471 | 2 / 3 | 3.1 | Yes |
383593 | luzindole | C19H20N2O | 292.382 | 1 / 2 | 3.6 | Yes |
405861 | CHEMBL394406 | C16H21BrN2O2 | 353.26 | 2 / 1 | 3.1 | Yes |
408815 | CHEMBL241928 | C16H20N2O | 256.349 | 1 / 1 | 2.3 | Yes |
410780 | CHEMBL243002 | C20H26N2O | 310.441 | 1 / 1 | 3.8 | Yes |
437295 | CHEMBL233311 | C19H20N2O2 | 308.381 | 2 / 2 | 3.2 | Yes |
439158 | CHEMBL233310 | C15H19BrN2O2 | 339.233 | 2 / 1 | 2.7 | Yes |
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