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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melatonin receptor type 1C
Species	Xenopus laevis (African clawed frog)
Gene	mtnr1c
Synonym	Mel-1C-R Mel1c (alpha) receptor Mel1c receptor
Disease	N/A for non-human GPCRs
Length	420
Amino acid sequence	MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR
UniProt	P49219
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5495
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL242573
Molecular formula	C18H22N2O
IUPAC name	N-[3-(1-azatricyclo[6.3.1.04,12]dodeca-2,4,6,8(12)-tetraen-3-yl)propyl]cyclopropanecarboxamide
Molecular weight	282.387
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	2.7
Synonyms	BDBM50423057
Inchi Key	LGMKHPBEFOPMIS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22N2O/c21-18(14-8-9-14)19-10-2-5-15-12-20-11-3-6-13-4-1-7-16(15)17(13)20/h1,4,7,12,14H,2-3,5-6,8-11H2,(H,19,21)
PubChem CID	16743124
ChEMBL	CHEMBL242573
IUPHAR	N/A
BindingDB	50423057
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1513.56 nM	PMID17346859	ChEMBL
IC50	1514.0 nM	PMID17346859	BindingDB

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