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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Trace amine-associated receptor 7b
Species	Rattus norvegicus (Rat)
Gene	Taar7b
Synonym	TaR-12 TaR-7b Trace amine receptor 12 Trace amine receptor 7b
Disease	N/A for non-human GPCRs
Length	358
Amino acid sequence	MATDDDRFPWDQDSILSRDLLSASSMQLCYEKLNRSCVRSPYSPGPRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADFLVGLTVMPFSMVRSVEGCWYFGDIYCKFHSSFDGSFCYSSIFHLCFISADRYIAVSDPLIYPTRFTASVSGKCITFSWLLSIIYSFSLFYTGVNEAGLEDLVSALTCVGGCQIAVNQSWVFINFLLFLVPALVMMTVYSKIFLIAKQQAQNIEKMGKQTARASESYKDRVAKRERKAAKTLGIAVAAFLLSWLPYFIDSIIDAFLGFVTPTYVYEILVWIGYYNSAMNPLIYAFFYPWFRKAIKLIVTGKILRENSSATNLFPE
UniProt	Q923X8
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2176813
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3641713
Molecular formula	C20H22N4O
IUPAC name	1-benzyl-N-[4-[(2S)-morpholin-2-yl]phenyl]pyrazol-3-amine
Molecular weight	334.423
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.7
Synonyms	SCHEMBL12609690 US8802673, 161 BDBM129519
Inchi Key	FECQBRYEGPGWBE-LJQANCHMSA-N
Inchi ID	InChI=1S/C20H22N4O/c1-2-4-16(5-3-1)15-24-12-10-20(23-24)22-18-8-6-17(7-9-18)19-14-21-11-13-25-19/h1-10,12,19,21H,11,13-15H2,(H,22,23)/t19-/m1/s1
PubChem CID	68325475
ChEMBL	CHEMBL3641713
IUPHAR	N/A
BindingDB	129519
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	222.9 nM	, None	BindingDB,ChEMBL

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