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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Homo sapiens (Human)
Gene	OPRM1
Synonym	hMOP M-OR-1 MOP opioid receptor, mu 1 opioid receptor MOPr MOR-1 Mu opiate receptor Mu opioid receptor mu receptor OP3 [ Show all ]
Disease	Diarrhea Inflammatory disease Pain Major depressive disorder Migraine Mild pain Moderate-to-severe acute pain Opioid-induced constipation Opiate dependence Urinary incontinence Movement disorder Obesity Non-small cell lung cancer Systemic pain Headache Analgesia Anesthesia Asthma Cancer pain Chronic pain Constipation Diabetic neuropathy Unspecified Gastrointestinal disease Gastrointestinal disease; Pain General anesthesia Narcotic depression [ Show all ]
Length	400
Amino acid sequence	MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
UniProt	P35372
Protein Data Bank	N/A
GPCR-HGmod model	P35372
3D structure model	This predicted structure model is from GPCR-EXP P35372.
BioLiP	N/A
Therapeutic Target Database	T47768
ChEMBL	CHEMBL233
IUPHAR	319
DrugBank	BE0000770

Ligand

Name	3-(2-Methylaminoethyl)indol-5-ol oxalate
Molecular formula	C13H16N2O5
IUPAC name	3-[2-(methylamino)ethyl]-1H-indol-5-ol;oxalic acid
Molecular weight	280.28
Hydrogen bond acceptor	6
Hydrogen bond donor	5
XlogP	None
Synonyms	J-012764 N-omega-Methyl-5-hydroxytryptamine oxalate salt NSC-91541 ST055634 AC1L6327 DTXSID80293695 MCULE-1823155663 NCGC00261428-01 N\|O-Methylserotonin oxalate salt 5-Hydroxy-N-omega-methyltryptamine, oxalate salt AKOS024282337 FT-0620492 HMS3262E08 N-Methylserotonin oxalate Nomega-Methyl-5-hydroxy??trypt??amine oxalate salt, >=98% (alkalimetric) SR-01000075980 1975-81-1 5-hydroxy-nw-methyltryptamine oxalate CHEMBL1256286 LP00743 N-omega-Methylserotonin NSC91541 Tox21_500743 3-[2-(methylamino)ethyl]-1H-indol-5-ol; oxalic acid AC1Q5RMG EINECS 239-611-4 MFCD00013159 Nomega'-Methyl-5-hydroxy trypt amine oxalate salt SCHEMBL1320479 5-Hydroxy-Nomega-methyltryptamine oxalate CCG-222047 H-7000 HMS3371J12 N-omega-METHYL-5-HYDROXYTRYPTAMINE Nomega-Methylserotonin oxalate salt SR-01000075980-1 3-(2-(Methylamino)ethyl)-1H-indol-5-ol oxalate 5-Hydroxy-N\|O-methyltryptamine oxalate CTK0I2793 M 1514 NCGC00094085-01 N\|O-Methyl-5-hydroxy-trypt-amine oxalate salt 3-[2-(methylamino)ethyl]indol-5-ol, ethanedioic acid ACM1975811 EU-0100743 HMS2234N19 MLS000859941 Nomega-Methyl-5-hydroxy-trypt-amine oxalate salt SMR000326801 15558-50-6 5-Hydroxy-Nomega-methyltryptamine oxalate, 99% [ Show all ]
Inchi Key	DYOZWAJOUTVNAF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)
PubChem CID	260390
ChEMBL	CHEMBL1256286
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	92407.0 nM	PubChem BioAssay data set	ChEMBL

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