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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 1D
Species	Sus scrofa (Pig)
Gene	HTR1D
Synonym	5-HT-1D 5-HT1D Serotonin receptor 1D
Disease	N/A for non-human GPCRs
Length	291
Amino acid sequence	AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
UniProt	P79400
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4105
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL262652
Molecular formula	C22H25N5O3S
IUPAC name	N-[4-[[5-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide
Molecular weight	439.534
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.1
Synonyms	SCHEMBL8786201 BDBM50406774
Inchi Key	DXMSFKTUXGYHFG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25N5O3S/c1-27(2)11-10-17-14-23-20-9-6-16(13-19(17)20)22-24-21(25-30-22)12-15-4-7-18(8-5-15)26-31(3,28)29/h4-9,13-14,23,26H,10-12H2,1-3H3
PubChem CID	9980618
ChEMBL	CHEMBL262652
IUPHAR	N/A
BindingDB	50406774
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1.259 nM	PMID8496922	ChEMBL
IC50	1.26 nM	PMID8496922	BindingDB

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