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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Growth hormone secretagogue receptor type 1
Species	Homo sapiens (Human)
Gene	GHSR
Synonym	ghrelin receptor GH-releasing peptide receptor GHRP GHS-R growth hormone-releasing peptide receptor ghrelin receptor 1a [ Show all ]
Disease	N/A
Length	366
Amino acid sequence	MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
UniProt	Q92847
Protein Data Bank	N/A
GPCR-HGmod model	Q92847
3D structure model	This predicted structure model is from GPCR-EXP Q92847.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4616
IUPHAR	246
DrugBank	BE0003383

Ligand

Name	CHEMBL185876
Molecular formula	C32H41FN4O2
IUPAC name	N-[2-(cyclohexylamino)-1-(4-fluorophenyl)-2-oxoethyl]-N-[3-(diethylamino)propyl]-5-phenyl-1H-pyrrole-2-carboxamide
Molecular weight	532.704
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	6.2
Synonyms	AC1Q2ZAM BDBM50151167 N-cyclohexyl-2-{N-[3-(diethylamino)propyl]-1-(5-phenyl-1H-pyrrol-2-yl)formamido}-2-(4-fluorophenyl)acetamide AKOS000772927 AC1MLJGG N-[2-(cyclohexylamino)-1-(4-fluorophenyl)-2-oxoethyl]-N-[3-(diethylamino)propyl]-5-phenyl-1H-pyrrole-2-carboxamide ASN 03651767 5-Phenyl-1H-pyrrole-2-carboxylic acid [cyclohexylcarbamoyl-(4-fluoro-phenyl)-methyl]-(3-diethylamino-propyl)-amide [ Show all ]
Inchi Key	AIYPAHQFSXORFN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H41FN4O2/c1-3-36(4-2)22-11-23-37(32(39)29-21-20-28(35-29)24-12-7-5-8-13-24)30(25-16-18-26(33)19-17-25)31(38)34-27-14-9-6-10-15-27/h5,7-8,12-13,16-21,27,30,35H,3-4,6,9-11,14-15,22-23H2,1-2H3,(H,34,38)
PubChem CID	3174463
ChEMBL	CHEMBL185876
IUPHAR	N/A
BindingDB	50151167
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	0.57 -	PMID15294000	ChEMBL
Ki	1290.0 nM	PMID15294000	BindingDB,ChEMBL

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