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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melanocortin receptor 3
Species	Homo sapiens (Human)
Gene	MC3R
Synonym	MC3-R melanocortin receptor 3 MC3 receptor gamma-MSH receptor
Disease	Sexual dysfunction; Obesity; Type 2 diabetes
Length	323
Amino acid sequence	MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
UniProt	P41968
Protein Data Bank	N/A
GPCR-HGmod model	P41968
3D structure model	This predicted structure model is from GPCR-EXP P41968.
BioLiP	N/A
Therapeutic Target Database	T76846
ChEMBL	CHEMBL4644
IUPHAR	284
DrugBank	N/A

Ligand

Name	CHEMBL8825
Molecular formula	C29H30N2O3
IUPAC name	6-[[naphthalen-1-ylmethyl(naphthalen-2-ylmethyl)carbamoyl]amino]hexanoic acid
Molecular weight	454.57
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.6
Synonyms	BDBM50111173 6-(3-Naphthalen-2-ylmethyl-3-naphthalen-1-ylmethyl-ureido)-hexanoic acid
Inchi Key	AIQVHEKDZNMUKX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H30N2O3/c32-28(33)15-2-1-7-18-30-29(34)31(20-22-16-17-23-9-3-4-11-25(23)19-22)21-26-13-8-12-24-10-5-6-14-27(24)26/h3-6,8-14,16-17,19H,1-2,7,15,18,20-21H2,(H,30,34)(H,32,33)
PubChem CID	44265374
ChEMBL	CHEMBL8825
IUPHAR	N/A
BindingDB	50111173
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	33000.0 nM	PMID11909711	BindingDB,ChEMBL

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