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GPCR

NameBeta-2 adrenergic receptor
SpeciesRattus norvegicus (Rat)
GeneAdrb2
Synonymbeta2-adrenoceptor
Beta-2 adrenoreceptor
Beta-2 adrenoceptor
beta-2 adrenergic receptor
beta 2-AR
[ Show all ]
DiseaseN/A for non-human GPCRs
Length418
Amino acid sequenceMEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
UniProtP10608
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3754
IUPHAR29
DrugBankN/A

Ligand

NameCHEMBL3230447
Molecular formulaC23H27NO8
IUPAC name5-[2-hydroxy-3-[2-(4-hydroxyphenyl)ethylamino]propoxy]-3,4-dihydro-2H-naphthalen-1-one;oxalic acid
Molecular weight445.468
Hydrogen bond acceptor9
Hydrogen bond donor5
XlogPNone
SynonymsN/A
Inchi KeyDJLCYXBGFZQZOW-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H25NO4.C2H2O4/c23-16-9-7-15(8-10-16)11-12-22-13-17(24)14-26-21-6-2-3-18-19(21)4-1-5-20(18)25;3-1(4)2(5)6/h2-3,6-10,17,22-24H,1,4-5,11-14H2;(H,3,4)(H,5,6)
PubChem CID12541315
ChEMBLCHEMBL3230447
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
Kapp0.56 uMPMID37339ChEMBL

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