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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1729987
Molecular formula	C21H21N3O4
IUPAC name	5-[(E)-hydroxyiminomethyl]-4-(4-methoxyphenoxy)-2-(4-propan-2-ylphenyl)pyridazin-3-one
Molecular weight	379.416
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.8
Synonyms	N/A
Inchi Key	DHWOMVXPTCGVCE-YDZHTSKRSA-N
Inchi ID	InChI=1S/C21H21N3O4/c1-14(2)15-4-6-17(7-5-15)24-21(25)20(16(12-22-24)13-23-26)28-19-10-8-18(27-3)9-11-19/h4-14,26H,1-3H3/b23-13+
PubChem CID	46835790
ChEMBL	CHEMBL1729987
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	16100.0 nM	PubChem BioAssay data set	ChEMBL

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