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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL54029
Molecular formula	C28H30N2O3
IUPAC name	(2E)-5,5-bis(4-methoxyphenyl)-N-(4-pyridin-3-ylbutyl)penta-2,4-dienamide
Molecular weight	442.559
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.7
Synonyms	(E)-5,5-bis(4-methoxyphenyl)-N-[4-(3-pyridinyl) butyl]-2,4-pentadienamide SCHEMBL9519484 BDBM50018380 DHEQLSFAAHXFEP-BJMVGYQFSA-N 5,5-Bis-(4-methoxy-phenyl)-penta-2,4-dienoic acid (4-pyridin-3-yl-butyl)-amide SCHEMBL9519479 [ Show all ]
Inchi Key	DHEQLSFAAHXFEP-BJMVGYQFSA-N
Inchi ID	InChI=1S/C28H30N2O3/c1-32-25-15-11-23(12-16-25)27(24-13-17-26(33-2)18-14-24)9-5-10-28(31)30-20-4-3-7-22-8-6-19-29-21-22/h5-6,8-19,21H,3-4,7,20H2,1-2H3,(H,30,31)/b10-5+
PubChem CID	14347337
ChEMBL	CHEMBL54029
IUPHAR	N/A
BindingDB	50018380
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
ID50	0.25 mg.kg-1	PMID2754709	ChEMBL
Inhibition	82.0 %	PMID2754709	ChEMBL

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