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Name | Somatostatin receptor type 5 |
---|---|
Species | Homo sapiens (Human) |
Gene | SSTR5 |
Synonym | SOMATO SS-5-R SS5-R SS5R SST5 receptor |
Disease | N/A |
Length | 364 |
Amino acid sequence | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL |
UniProt | P35346 |
Protein Data Bank | N/A |
GPCR-HGmod model | P35346 |
3D structure model | This predicted structure model is from GPCR-EXP P35346. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1792 |
IUPHAR | 359 |
DrugBank | BE0002147 |
Name | BDBM82466 |
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Molecular formula | C55H68ClN9O8 |
IUPAC name | (3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3,15-dibenzyl-18-[(4-chlorophenyl)methyl]-6-[(1R)-1-hydroxyethyl]-12-(1H-indol-3-ylmethyl)-1,4,7,10,13,16,19-heptazacyclohexacosane-2,5,8,11,14,17,20-heptone |
Molecular weight | 1018.65 |
Hydrogen bond acceptor | 9 |
Hydrogen bond donor | 10 |
XlogP | 6.2 |
Synonyms | L-362,862 L-362862 c[Aha-Phe-p-C1-Phe-D-Trp-Lys-Thr-Phe] |
Inchi Key | DFYIJRIFNXQXAY-FHTVTOFSSA-N |
Inchi ID | InChI=1S/C55H68ClN9O8/c1-35(66)49-55(73)64-44(30-36-16-6-4-7-17-36)50(68)58-29-15-3-2-10-23-48(67)60-45(32-38-24-26-40(56)27-25-38)52(70)62-46(31-37-18-8-5-9-19-37)53(71)63-47(33-39-34-59-42-21-12-11-20-41(39)42)54(72)61-43(51(69)65-49)22-13-14-28-57/h4-9,11-12,16-21,24-27,34-35,43-47,49,59,66H,2-3,10,13-15,22-23,28-33,57H2,1H3,(H,58,68)(H,60,67)(H,61,72)(H,62,70)(H,63,71)(H,64,73)(H,65,69)/t35-,43+,44+,45+,46+,47-,49+/m1/s1 |
PubChem CID | 57339672 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 82466 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 44.0 nM | PMID8102785 | BindingDB |
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