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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Oryctolagus cuniculus (Rabbit)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
UniProt	P34976
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3948
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL343723
Molecular formula	C31H39N4O11PS
IUPAC name	(2S,4S)-4-[4-(2-phosphonoethyl)phenoxy]-1-[(2R)-2-[4-[(2-sulfobenzoyl)amino]imidazol-1-yl]octanoyl]pyrrolidine-2-carboxylic acid
Molecular weight	706.704
Hydrogen bond acceptor	12
Hydrogen bond donor	5
XlogP	2.4
Synonyms	(2S,4S)-4-[4-(2-Phosphonoethyl)phenoxy]-1-[(R)-2-[4-[(2-sulfobenzoyl)amino]-1H-imidazol-1-yl]octanoyl]pyrrolidine-2-carboxylic acid
Inchi Key	AHVBCXNTEARNKF-DMDYGQEQSA-N
Inchi ID	InChI=1S/C31H39N4O11PS/c1-2-3-4-5-9-25(34-19-28(32-20-34)33-29(36)24-8-6-7-10-27(24)48(43,44)45)30(37)35-18-23(17-26(35)31(38)39)46-22-13-11-21(12-14-22)15-16-47(40,41)42/h6-8,10-14,19-20,23,25-26H,2-5,9,15-18H2,1H3,(H,33,36)(H,38,39)(H2,40,41,42)(H,43,44,45)/t23-,25+,26-/m0/s1
PubChem CID	10395020
ChEMBL	CHEMBL343723
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Kb	0.4 nM	PMID7799401	ChEMBL

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