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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melanin-concentrating hormone receptor 2
Species	Homo sapiens (Human)
Gene	MCHR2
Synonym	G-protein coupled receptor 145 melanin-concentrating hormone receptor 2 MCHR-2 MCH2R MCH2 receptor MCH2 G protein-coupled receptor 145 MCH-2R MCH receptor 2 GPRv17 GPR145 MCH-R2 [ Show all ]
Disease	N/A
Length	340
Amino acid sequence	MNPFHASCWNTSAELLNKSWNKEFAYQTASVVDTVILPSMIGIICSTGLVGNILIVFTIIRSRKKTVPDIYICNLAVADLVHIVGMPFLIHQWARGGEWVFGGPLCTIITSLDTCNQFACSAIMTVMSVDRYFALVQPFRLTRWRTRYKTIRINLGLWAASFILALPVWVYSKVIKFKDGVESCAFDLTSPDDVLWYTLYLTITTFFFPLPLILVCYILILCYTWEMYQQNKDARCCNPSVPKQRVMKLTKMVLVLVVVFILSAAPYHVIQLVNLQMEQPTLAFYVGYYLSICLSYASSSINPFLYILLSGNFQKRLPQIQRRATEKEINNMGNTLKSHF
UniProt	Q969V1
Protein Data Bank	N/A
GPCR-HGmod model	Q969V1
3D structure model	This predicted structure model is from GPCR-EXP Q969V1.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5038
IUPHAR	281
DrugBank	N/A

Ligand

Name	CHEMBL182554
Molecular formula	C29H34N4O4
IUPAC name	2-methoxy-4-[(4-phenoxyphenyl)carbamoylamino]-N-(3-piperidin-1-ylpropyl)benzamide
Molecular weight	502.615
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.5
Synonyms	BDBM50153206 SCHEMBL6108873 2-Methoxy-4-[3-(4-phenoxy-phenyl)-ureido]-N-(3-piperidin-1-yl-propyl)-benzamide
Inchi Key	DCMOVMXTFVOSNS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H34N4O4/c1-36-27-21-23(13-16-26(27)28(34)30-17-8-20-33-18-6-3-7-19-33)32-29(35)31-22-11-14-25(15-12-22)37-24-9-4-2-5-10-24/h2,4-5,9-16,21H,3,6-8,17-20H2,1H3,(H,30,34)(H2,31,32,35)
PubChem CID	9806086
ChEMBL	CHEMBL182554
IUPHAR	N/A
BindingDB	50153206
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<100000.0 nM	PMID15380202	BindingDB,ChEMBL
IC50	10000.0 nM	PMID15380202	BindingDB,ChEMBL

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