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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cysteinyl leukotriene receptor 2
Species	Homo sapiens (Human)
Gene	CYSLTR2
Synonym	CysLTR2 CysLT2 receptor LTC4 HPN321 hGPCR21 HG57 G-protein coupled receptor HG57 CYSLT2R G-protein coupled receptor GPCR21 [ Show all ]
Disease	Unspecified Asthma
Length	346
Amino acid sequence	MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV
UniProt	Q9NS75
Protein Data Bank	N/A
GPCR-HGmod model	Q9NS75
3D structure model	This predicted structure model is from GPCR-EXP Q9NS75.
BioLiP	N/A
Therapeutic Target Database	T74238
ChEMBL	CHEMBL4330
IUPHAR	270
DrugBank	BE0000099

Ligand

Name	CHEMBL2413379
Molecular formula	C30H38O7
IUPAC name	4-(carboxymethoxy)-3-[(E)-3-(3-dodecoxyphenyl)prop-2-enoyl]benzoic acid
Molecular weight	510.627
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	8.3
Synonyms	N/A
Inchi Key	DBSKFJPBQIDDDV-BMRADRMJSA-N
Inchi ID	InChI=1S/C30H38O7/c1-2-3-4-5-6-7-8-9-10-11-19-36-25-14-12-13-23(20-25)15-17-27(31)26-21-24(30(34)35)16-18-28(26)37-22-29(32)33/h12-18,20-21H,2-11,19,22H2,1H3,(H,32,33)(H,34,35)/b17-15+
PubChem CID	71654672
ChEMBL	CHEMBL2413379
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	250.0 nM	PMID23455026	ChEMBL
Imax	80.5 %	PMID23455026	ChEMBL
Inhibition	70.5 %	PMID23455026	ChEMBL

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