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Name | Probable G-protein coupled receptor 174 |
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Species | Homo sapiens (Human) |
Gene | GPR174 |
Synonym | FKSG79 GPR174 |
Disease | N/A |
Length | 333 |
Amino acid sequence | MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC |
UniProt | Q9BXC1 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9BXC1 |
3D structure model | This predicted structure model is from GPCR-EXP Q9BXC1. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562167 |
IUPHAR | 145 |
DrugBank | N/A |
Name | lysophosphatidylserine |
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Molecular formula | C24H48NO9P |
IUPAC name | (2S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-octadecanoyloxypropoxy]phosphoryl]oxypropanoic acid |
Molecular weight | 525.62 |
Hydrogen bond acceptor | 10 |
Hydrogen bond donor | 4 |
XlogP | 3.1 |
Synonyms | 1-octadecanoyl-sn-glycero-3-phosphoserine LMGP03050006 ZINC49722989 (2S)-2-amino-3-[hydroxy-[(2R)-2-hydroxy-3-octadecanoyloxypropoxy]phosphoryl]oxypropanoic acid D0M8IT [ Show all ] |
Inchi Key | ZPDQFUYPBVXUKS-YADHBBJMSA-N |
Inchi ID | InChI=1S/C24H48NO9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(27)32-18-21(26)19-33-35(30,31)34-20-22(25)24(28)29/h21-22,26H,2-20,25H2,1H3,(H,28,29)(H,30,31)/t21-,22+/m1/s1 |
PubChem CID | 42607474 |
ChEMBL | N/A |
IUPHAR | 4064 |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 81.0 nM | PMID22983457 | IUPHAR |
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