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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	G-protein coupled receptor 87
Species	Homo sapiens (Human)
Gene	GPR87
Synonym	FKSG78 G-protein coupled receptor 95 GPR87 GPR95
Disease	N/A
Length	358
Amino acid sequence	MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV
UniProt	Q9BY21
Protein Data Bank	N/A
GPCR-HGmod model	Q9BY21
3D structure model	This predicted structure model is from GPCR-EXP Q9BY21.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	122
DrugBank	N/A

Ligand

Name	lysophosphatidic acid
Molecular formula	C21H41O7P
IUPAC name	(2-hydroxy-3-phosphonooxypropyl) (Z)-octadec-9-enoate
Molecular weight	436.526
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	5.2
Synonyms	D0X0UR monooleylphosphatidate [3H]-LPA (2-hydroxy-3-phosphonooxypropyl) (E)-octadec-9-enoic acid 1-Oleoyl-lyso-phosphatidic acid 9-octadecenoic acid, 2-hydroxy-3-(phosphonooxy)propyl ester, (9Z)- EINECS 244-710-0 Olein, 1-mono-, 3-phosphate (7CI) [3H]lysophosphatidic acid 1-monooleoylglycerol 3-phosphate 1-Oleyllysophosphatidate cis-9-Octadecenoic acid 2-hydroxy-3-phosphonooxypropyl ester SCHEMBL1548 1-oleoyl-LPA 2-Hydroxy-3-(phosphonooxy)propyl oleate D0Z9FO Monooleylphosphatidic acid [3H]1-oleoyl-LPA (2-hydroxy-3-phosphonooxypropyl) (Z)-octadec-9-enoate 1-Oleoyl-lysophosphatidate 9-Octadecenoic acid (9Z)-, 2-hydroxy-3-(phosphonooxy)propyl ester (9CI) AC1NUZKL GTPL2906 Oleoyl lysophosphatidate {2-hydroxy-3-[(9Z)-octadec-9-enoyloxy]propoxy}phosphonic acid 1-Oleoyl-2-lysophosphatidic acid 1-Oleyllysophosphatidic acid CMC_8485 Lysophosphophatidic acid WRGQSWVCFNIUNZ-KTKRTIGZSA-N (2-hydroxy-3-phosphonooxypropyl) (E)-octadec-9-enoate 1-Oleoyl-lyso-phosphatidate 22002-87-5 DTXSID5041061 Olein, 1-mono-, 3-(dihydrogen phosphate) (8CI) [3H]LPA 1-(9Z-octadecenoyl)-phosphatidic acid 1-oleoyl-lysophosphatidic acid 9-Octadecenoic acid (Z)-, 2-hydroxy-3-(phosphonooxy)propyl ester AKOS030561932 GTPL5395 Oleoyl lysophosphatidic acid 1-oleoyl-glycero-3-phosphate 2-hydroxy-3-(phosphonooxy)propyl (9Z)-octadec-9-enoate [ Show all ]
Inchi Key	WRGQSWVCFNIUNZ-KTKRTIGZSA-N
Inchi ID	InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-
PubChem CID	5497152
ChEMBL	N/A
IUPHAR	2906
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	36.3078 nM	PMID17905198, PMID18466763	IUPHAR

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