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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 6
Species	Homo sapiens (Human)
Gene	LPAR6
Synonym	Purinergic receptor 5 P2Y5 P2Y purinoceptor 5 P2RY5 oleoyl-L-alpha-lysophosphatidic acid receptor LPA6 receptor LPA-6 LPA receptor 6 RB intron encoded G-protein coupled receptor [ Show all ]
Disease	N/A
Length	344
Amino acid sequence	MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDFRFSEVHGAENFIQHNLQTLKSKIFDNESAA
UniProt	P43657
Protein Data Bank	N/A
GPCR-HGmod model	P43657
3D structure model	This predicted structure model is from GPCR-EXP P43657.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2331058
IUPHAR	163
DrugBank	N/A

Ligand

Name	lysophosphatidic acid
Molecular formula	C21H41O7P
IUPAC name	(2-hydroxy-3-phosphonooxypropyl) (Z)-octadec-9-enoate
Molecular weight	436.526
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	5.2
Synonyms	monooleylphosphatidate [3H]-LPA (2-hydroxy-3-phosphonooxypropyl) (E)-octadec-9-enoic acid 1-Oleoyl-lyso-phosphatidic acid D0X0UR Olein, 1-mono-, 3-phosphate (7CI) [3H]lysophosphatidic acid 1-monooleoylglycerol 3-phosphate 1-Oleyllysophosphatidate 9-octadecenoic acid, 2-hydroxy-3-(phosphonooxy)propyl ester, (9Z)- EINECS 244-710-0 SCHEMBL1548 1-oleoyl-LPA 2-Hydroxy-3-(phosphonooxy)propyl oleate cis-9-Octadecenoic acid 2-hydroxy-3-phosphonooxypropyl ester Monooleylphosphatidic acid [3H]1-oleoyl-LPA (2-hydroxy-3-phosphonooxypropyl) (Z)-octadec-9-enoate 1-Oleoyl-lysophosphatidate 9-Octadecenoic acid (9Z)-, 2-hydroxy-3-(phosphonooxy)propyl ester (9CI) D0Z9FO GTPL2906 Oleoyl lysophosphatidate {2-hydroxy-3-[(9Z)-octadec-9-enoyloxy]propoxy}phosphonic acid 1-Oleoyl-2-lysophosphatidic acid 1-Oleyllysophosphatidic acid AC1NUZKL Lysophosphophatidic acid WRGQSWVCFNIUNZ-KTKRTIGZSA-N (2-hydroxy-3-phosphonooxypropyl) (E)-octadec-9-enoate 1-Oleoyl-lyso-phosphatidate 22002-87-5 CMC_8485 Olein, 1-mono-, 3-(dihydrogen phosphate) (8CI) [3H]LPA 1-(9Z-octadecenoyl)-phosphatidic acid 1-oleoyl-lysophosphatidic acid 9-Octadecenoic acid (Z)-, 2-hydroxy-3-(phosphonooxy)propyl ester DTXSID5041061 GTPL5395 Oleoyl lysophosphatidic acid 1-oleoyl-glycero-3-phosphate 2-hydroxy-3-(phosphonooxy)propyl (9Z)-octadec-9-enoate AKOS030561932 [ Show all ]
Inchi Key	WRGQSWVCFNIUNZ-KTKRTIGZSA-N
Inchi ID	InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-
PubChem CID	5497152
ChEMBL	N/A
IUPHAR	2906
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1000.0 nM	PMID19386608, PMID18297070	IUPHAR

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