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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Oxoeicosanoid receptor 1
Species	Homo sapiens (Human)
Gene	OXER1
Synonym	R527 oxoeicosanoid (OXE) receptor 1 OXE receptor hGPCR48 GPR170 G-protein coupled receptor TG1019 G-protein coupled receptor R527 G-protein coupled receptor 170 5-oxo-ETE receptor 5-oxo-ETE G-protein coupled receptor TG1019 [ Show all ]
Disease	N/A
Length	423
Amino acid sequence	MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
UniProt	Q8TDS5
Protein Data Bank	N/A
GPCR-HGmod model	Q8TDS5
3D structure model	This predicted structure model is from GPCR-EXP Q8TDS5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1628461
IUPHAR	271
DrugBank	N/A

Ligand

Name	Gue 1654
Molecular formula	C23H17N3OS3
IUPAC name	N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-2,2-diphenylacetamide
Molecular weight	447.589
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.5
Synonyms	AC1NNCON Gue1654, >=98% (HPLC) SR-01000445495 F0817-0134 N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-2,2-di(phenyl)acetamide 7-(Methylthio)-2-[(2,2-diphenylacetyl)amino]benzo[1,2-d:4,3-d']bisthiazole N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-?-phenylbenzeneacetamide AKOS024458320 MCULE-6542059725 SR-01000445495-1 397290-30-1 Glue-1654 N-(2-methylsulfanyl-[1,3]thiazolo[4,5-g][1,3]benzothiazol-7-yl)-2,2-diphenylacetamide AB00138664-02 Gue1654 Oprea1_451472 D0T0HS MolPort-003-055-398 ZINC11852816 GTPL6173 N-(7-(methylthio)benzo[1,2-d:4,3-d']bis(thiazole)-2-yl)-2,2-diphenylacetamide [ Show all ]
Inchi Key	UFOBDFMYJABXGK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H17N3OS3/c1-28-23-25-17-13-12-16-19(20(17)30-23)29-22(24-16)26-21(27)18(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-13,18H,1H3,(H,24,26,27)
PubChem CID	5066134
ChEMBL	N/A
IUPHAR	6173
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1000.0 nM	PMID22634634	IUPHAR

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