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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Probable G-protein coupled receptor 132
Species	Homo sapiens (Human)
Gene	GPR132
Synonym	G protein-coupled receptor G2A G2 accumulation protein GPR132
Disease	N/A
Length	380
Amino acid sequence	MCPMLLKNGYNGNATPVTTTAPWASLGLSAKTCNNVSFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLALCELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCISCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQTEDKETCFDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQKAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGDRNAMCGLEERLYTASVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLTHSRDTEELQSPVALADHYTFSRPVHPPGSPCPAKRLIEESC
UniProt	Q9UNW8
Protein Data Bank	N/A
GPCR-HGmod model	Q9UNW8
3D structure model	This predicted structure model is from GPCR-EXP Q9UNW8.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3085618
IUPHAR	128
DrugBank	N/A

Ligand

Name	9(S)-HODE
Molecular formula	C18H32O3
IUPAC name	(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
Molecular weight	296.451
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.3
Synonyms	(9S)-Hydroxyoctadecadienoic acid 42KE04U9BM 9HO alpha-Dimorphecolic acid, (9S)- DB07302 SR-01000946948-1 (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoate 9S-hydroxy-10E,12Z-octadecadienoic acid C14767 IDI1_033955 [S-(E,Z)]-9-hydroxy-10,12-Octadecadienoate (10E,12Z)-(9S)-9-Hydroxyoctadeca-10,12-dienoic acid 10,12-Octadecadienoic acid, 9-hydroxy-, [S-(E,Z)]- 9(S)-hydroxyoctadecadienoic acid alpha-dimorphecolic acid D0C2DG SCHEMBL3188979 (9S)-Hydroxyoctadecadinoiec acid 9S-HODE BCBcMAP01_000085 GTPL5567 UNII-42KE04U9BM (+)-alpha-Dimorphecolic acid (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid 9(S)-HODE, >=98% (HPLC) AC1NSNNN CHEBI:34496 LMFA02000188 [S-(E,Z)]-9-hydroxy-10,12-Octadecadienoic acid (9S)-Hydroxyoctadecadienoate 1530AH 9-hydroxyoctadecadienoic acid alpha-Dimorphecolic acid, (+)- D0SZ4T SR-01000946948 (9s,10e,12z)-9-hydroxy-10,12-octadecadienoic acid 73543-67-6 9S-hydroxy-10E,12Z-octadecadienoate BML2-D04 HMS1361K07 ZINC4655401 (10E,12Z)-(9S)-9-Hydroxyoctadeca-10,12-dienoate 10,12-Octadecadienoic acid, 9-hydroxy-, (9S,10E,12Z)- 9(S)-Hydroxy-10(E),12(Z)-octadecadienoic acid Alpha-dimorphecolic CHEMBL1230670 NCGC00161316-01 [ Show all ]
Inchi Key	NPDSHTNEKLQQIJ-UINYOVNOSA-N
Inchi ID	InChI=1S/C18H32O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14,17,19H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6-,14-11+/t17-/m1/s1
PubChem CID	5312830
ChEMBL	N/A
IUPHAR	5567
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	2000.0 nM	PMID16236715	IUPHAR

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