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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 84
Species	Homo sapiens (Human)
Gene	GPR84
Synonym	GPCR4 GPR84 Inflammation-related G-protein coupled receptor EX33
Disease	N/A
Length	396
Amino acid sequence	MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
UniProt	Q9NQS5
Protein Data Bank	N/A
GPCR-HGmod model	Q9NQS5
3D structure model	This predicted structure model is from GPCR-EXP Q9NQS5.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3714079
IUPHAR	120
DrugBank	N/A

Ligand

Name	3-Hydroxydecanoic acid
Molecular formula	C10H20O3
IUPAC name	3-hydroxydecanoic acid
Molecular weight	188.267
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.5
Synonyms	CHEBI:132983 DL-beta-Hydroxycapric acid LMFA01050153 ( inverted exclamation markA)-3-Hydroxydecanoic acid 10:0(3-OH) 3-HYDROXYCAPRIC ACID AC1L1BIC D,L-B-Hydroxycapric Acid FYSSBMZUBSBFJL-UHFFFAOYSA-N Myrmicacin (+/-)-3-Hydroxy-decanoic Acid 1639952-40-1 3-OH-C10 AKOS011680873 Decanoic acid, 3-hydroxy-, (+-)- KB-125180 SS-4996 (+/-)3-hydroxy-decanoate 3-hydroxy-decanoate Beta-hydroxydecanoate CS-0059457 DL-\|A-Hydroxycapric acid MFCD00133275 (+-)-3-Hydroxydecanoic acid 1111092-37-5 3-Hydroxydecanoate ACMC-1BNWN D03GHN GTPL5848 rac 3-Hydroxydecanoic Acid (+/-)-3-Hydroxydecanoic acid 3-HDA 33044-91-6 AX8087331 beta-Hydroxydecanoic acid Decanoic acid,3-hydroxy- KS-000000R4 ST24042215 (+/-)3-hydroxy-decanoic acid 3-Hydroxy-decanoic acid A74EFF12-378B-4657-9726-F37DBE2A9013 CTK1H0157 FT-0669509 MolPort-003-889-285 (+/-)-3 -Hydroxy-decanoic Acid 14292-26-3 AK140664 Decanoic acid, 3-hydroxy- HY-113057 SCHEMBL155391 (+/-)-3-Hydroxydecanoic acid, >=98% 3-hydroxy capric acid 5561-87-5 beta-hydroxycapric acid [ Show all ]
Inchi Key	FYSSBMZUBSBFJL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C10H20O3/c1-2-3-4-5-6-7-9(11)8-10(12)13/h9,11H,2-8H2,1H3,(H,12,13)
PubChem CID	26612
ChEMBL	N/A
IUPHAR	5848
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
EC50	230000.0 nM	PMID23449982	IUPHAR

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