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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Neuropeptides B/W receptor type 1
Species	Homo sapiens (Human)
Gene	NPBWR1
Synonym	G protein-coupled receptor 7 G-protein coupled receptor 7 GPR7 neuropeptides B/W receptor type 1 NPBW1 receptor
Disease	N/A
Length	328
Amino acid sequence	MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
UniProt	P48145
Protein Data Bank	N/A
GPCR-HGmod model	P48145
3D structure model	This predicted structure model is from GPCR-EXP P48145.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1293293
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL1992695
Molecular formula	C19H13Cl3N2O4
IUPAC name	5-chloro-2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-4-(4-methoxyphenoxy)pyridazin-3-one
Molecular weight	439.673
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.7
Synonyms	SR-02000001264 SR-02000001264-1
Inchi Key	DAIZAQYOXCJXEB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H13Cl3N2O4/c1-27-12-3-5-13(6-4-12)28-18-16(22)9-23-24(19(18)26)10-17(25)14-7-2-11(20)8-15(14)21/h2-9H,10H2,1H3
PubChem CID	53234168
ChEMBL	CHEMBL1992695
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	1850.0 nM	PubChem BioAssay data set	ChEMBL

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