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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	CHEMBL3975980
Molecular formula	C24H22FNO4
IUPAC name	4-[[[4-(2-fluorophenoxy)benzoyl]-propylamino]methyl]benzoic acid
Molecular weight	407.441
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.9
Synonyms	ZINC584598367 BDBM251724 SCHEMBL16506501 US9464060, 60
Inchi Key	SOSAKGSLKXKLFU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H22FNO4/c1-2-15-26(16-17-7-9-19(10-8-17)24(28)29)23(27)18-11-13-20(14-12-18)30-22-6-4-3-5-21(22)25/h3-14H,2,15-16H2,1H3,(H,28,29)
PubChem CID	117902935
ChEMBL	CHEMBL3975980
IUPHAR	N/A
BindingDB	251724
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	60.0 nM	, None	BindingDB,ChEMBL

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