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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 4
Species	Cavia porcellus (Guinea pig)
Gene	HTR4
Synonym	5-HT-4 5-HT4 Serotonin receptor 4
Disease	N/A for non-human GPCRs
Length	388
Amino acid sequence	MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRPQPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDTVECGGQWESQCHPAASSPLVAAQPIDT
UniProt	O70528
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5017
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL143582
Molecular formula	C20H20N4O2
IUPAC name	2-(5-hydroxy-1H-indol-3-yl)-N'-[2-(5-hydroxy-1H-indol-3-yl)ethyl]ethanimidamide
Molecular weight	348.406
Hydrogen bond acceptor	3
Hydrogen bond donor	5
XlogP	2.3
Synonyms	N/A
Inchi Key	CZEQZLUEZALYQG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N4O2/c21-20(7-13-11-24-19-4-2-15(26)9-17(13)19)22-6-5-12-10-23-18-3-1-14(25)8-16(12)18/h1-4,8-11,23-26H,5-7H2,(H2,21,22)
PubChem CID	15681426
ChEMBL	CHEMBL143582
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
pD2	6.3 -	Bioorg. Med. Chem. Lett., (1992) 2:5:461	ChEMBL

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