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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	CHEMBL3985727
Molecular formula	C25H24FNO5
IUPAC name	4-[[[4-(4-fluoro-2-methoxyphenoxy)benzoyl]-propylamino]methyl]benzoic acid
Molecular weight	437.467
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	US9464060, 80 ZINC584598301 BDBM251744 SCHEMBL16507571
Inchi Key	LJTQGSYFZPTOOH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H24FNO5/c1-3-14-27(16-17-4-6-19(7-5-17)25(29)30)24(28)18-8-11-21(12-9-18)32-22-13-10-20(26)15-23(22)31-2/h4-13,15H,3,14,16H2,1-2H3,(H,29,30)
PubChem CID	117903728
ChEMBL	CHEMBL3985727
IUPHAR	N/A
BindingDB	251744
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	45.0 nM	, None	BindingDB,ChEMBL

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