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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	CHEMBL3961807
Molecular formula	C27H27NO4
IUPAC name	4-[[cyclobutylmethyl-[4-(2-methylphenoxy)benzoyl]amino]methyl]benzoic acid
Molecular weight	429.516
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.6
Synonyms	ZINC584598192 BDBM251687 SCHEMBL16506872 US9464060, 23
Inchi Key	DYBZGLVYMXXJHF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27NO4/c1-19-5-2-3-8-25(19)32-24-15-13-22(14-16-24)26(29)28(17-20-6-4-7-20)18-21-9-11-23(12-10-21)27(30)31/h2-3,5,8-16,20H,4,6-7,17-18H2,1H3,(H,30,31)
PubChem CID	117903241
ChEMBL	CHEMBL3961807
IUPHAR	N/A
BindingDB	251687
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	44.0 nM	, None	BindingDB,ChEMBL

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