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Name | C-X-C chemokine receptor type 5 |
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Species | Homo sapiens (Human) |
Gene | CXCR5 |
Synonym | BLR-1 NLR neurolymphatic receptor Monocyte-derived receptor 15 MDR15 [ Show all ] |
Disease | Systemic lupus erythematosus |
Length | 372 |
Amino acid sequence | MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF |
UniProt | P32302 |
Protein Data Bank | N/A |
GPCR-HGmod model | P32302 |
3D structure model | This predicted structure model is from GPCR-EXP P32302. |
BioLiP | N/A |
Therapeutic Target Database | T09528 |
ChEMBL | CHEMBL1075315 |
IUPHAR | N/A |
DrugBank | N/A |
Name | SCHEMBL3309198 |
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Molecular formula | C17H23NO4S |
IUPAC name | 4-[(3-methyl-2-propan-2-yloxybenzoyl)amino]thiane-4-carboxylic acid |
Molecular weight | 337.434 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 2 |
XlogP | 2.9 |
Synonyms | CHEMBL3717131 4-(2-Isopropoxy-3-methyl-benzoylamino)-tetrahydro-thiopyran-4-carboxylic acid WJRJYMFQPCHTNH-UHFFFAOYSA-N |
Inchi Key | WJRJYMFQPCHTNH-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C17H23NO4S/c1-11(2)22-14-12(3)5-4-6-13(14)15(19)18-17(16(20)21)7-9-23-10-8-17/h4-6,11H,7-10H2,1-3H3,(H,18,19)(H,20,21) |
PubChem CID | 59314148 |
ChEMBL | CHEMBL3717131 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 24000.0 nM | None | ChEMBL |
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