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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	C-X-C chemokine receptor type 5
Species	Homo sapiens (Human)
Gene	CXCR5
Synonym	BLR-1 NLR neurolymphatic receptor Monocyte-derived receptor 15 MDR15 MDR-15 Gpcr6 CXCR5 CXCR-5 CXC-R5 CD185 Burkitt lymphoma receptor 1 [ Show all ]
Disease	Systemic lupus erythematosus
Length	372
Amino acid sequence	MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF
UniProt	P32302
Protein Data Bank	N/A
GPCR-HGmod model	P32302
3D structure model	This predicted structure model is from GPCR-EXP P32302.
BioLiP	N/A
Therapeutic Target Database	T09528
ChEMBL	CHEMBL1075315
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL3309817
Molecular formula	C19H16N2O3
IUPAC name	2-(1H-indole-7-carbonylamino)-1,3-dihydroindene-2-carboxylic acid
Molecular weight	320.348
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.8
Synonyms	CHEMBL3717502 2-[(1H-Indole-7-carbonyl)-amino]-indan-2-carboxylic acid PJKRNEGHECUKBK-UHFFFAOYSA-N
Inchi Key	PJKRNEGHECUKBK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16N2O3/c22-17(15-7-3-6-12-8-9-20-16(12)15)21-19(18(23)24)10-13-4-1-2-5-14(13)11-19/h1-9,20H,10-11H2,(H,21,22)(H,23,24)
PubChem CID	59314233
ChEMBL	CHEMBL3717502
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<30000.0 nM	None	ChEMBL

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