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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Rattus norvegicus (Rat)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGAEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30680
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2978
IUPHAR	356
DrugBank	N/A

Ligand

Name	CHEMBL3144293
Molecular formula	C58H79IN10O17S3
IUPAC name	(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxy-3-(123I)iodanylphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-[[(2S)-3-phenyl-2-[3-[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylpropanoylamino]propanoyl]amino]-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
Molecular weight	1407.41
Hydrogen bond acceptor	21
Hydrogen bond donor	18
XlogP	0.0
Synonyms	N/A
Inchi Key	CWSQNDPKRNEXNE-NFDYHLBKSA-N
Inchi ID	InChI=1S/C58H79IN10O17S3/c1-29(72)41(25-70)66-56(84)43-28-89-88-27-42(67-52(80)38(21-31-10-4-3-5-11-31)62-46(75)17-19-87-58-50(78)49(77)48(76)45(26-71)86-58)55(83)64-39(22-32-15-16-44(74)35(59)20-32)53(81)65-40(23-33-24-61-36-13-7-6-12-34(33)36)54(82)63-37(14-8-9-18-60)51(79)69-47(30(2)73)57(85)68-43/h3-7,10-13,15-16,20,24,29-30,37-43,45,47-50,58,61,70-74,76-78H,8-9,14,17-19,21-23,25-28,60H2,1-2H3,(H,62,75)(H,63,82)(H,64,83)(H,65,81)(H,66,84)(H,67,80)(H,68,85)(H,69,79)/t29-,30-,37+,38+,39+,40-,41+,42+,43+,45+,47+,48+,49+,50+,58+/m1/s1/i59-4
PubChem CID	90663881
ChEMBL	CHEMBL3144293
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
ID/g	22.6 %	PMID15828816	ChEMBL

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