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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 6
Species	Homo sapiens (Human)
Gene	GPR6
Synonym	GPR6 Sphingosine 1-phosphate receptor GPR6
Disease	N/A
Length	362
Amino acid sequence	MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEV
UniProt	P46095
Protein Data Bank	N/A
GPCR-HGmod model	P46095
3D structure model	This predicted structure model is from GPCR-EXP P46095.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3714130
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL7084798
Molecular formula	C15H13N3OS2
IUPAC name	N-(2-sulfanylideneimidazolidine-1-carbothioyl)naphthalene-1-carboxamide
Molecular weight	315.409
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.8
Synonyms	CHEMBL3718165
Inchi Key	DTCMRPVOJDZFKN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H13N3OS2/c19-13(17-15(21)18-9-8-16-14(18)20)12-7-3-5-10-4-1-2-6-11(10)12/h1-7H,8-9H2,(H,16,20)(H,17,19,21)
PubChem CID	9966680
ChEMBL	CHEMBL3718165
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	100000.0 nM	None	ChEMBL
IC50	200000.0 nM	None	ChEMBL

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