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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	C-X-C chemokine receptor type 5
Species	Homo sapiens (Human)
Gene	CXCR5
Synonym	BLR-1 NLR neurolymphatic receptor Monocyte-derived receptor 15 MDR15 MDR-15 Gpcr6 CXCR5 CXCR-5 CXC-R5 CD185 Burkitt lymphoma receptor 1 [ Show all ]
Disease	Systemic lupus erythematosus
Length	372
Amino acid sequence	MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF
UniProt	P32302
Protein Data Bank	N/A
GPCR-HGmod model	P32302
3D structure model	This predicted structure model is from GPCR-EXP P32302.
BioLiP	N/A
Therapeutic Target Database	T09528
ChEMBL	CHEMBL1075315
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL3307137
Molecular formula	C19H16N2O4S
IUPAC name	2-(quinolin-8-ylsulfonylamino)-1,3-dihydroindene-2-carboxylic acid
Molecular weight	368.407
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.6
Synonyms	CHEMBL3717043 2-(Quinoline-8-sulfonylamino)-indan-2-carboxylic acid CYRHJONSAVCYDA-UHFFFAOYSA-N
Inchi Key	CYRHJONSAVCYDA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H16N2O4S/c22-18(23)19(11-14-5-1-2-6-15(14)12-19)21-26(24,25)16-9-3-7-13-8-4-10-20-17(13)16/h1-10,21H,11-12H2,(H,22,23)
PubChem CID	59314355
ChEMBL	CHEMBL3717043
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<30000.0 nM	None	ChEMBL

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