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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	G-protein coupled receptor 6
Species	Homo sapiens (Human)
Gene	GPR6
Synonym	GPR6 Sphingosine 1-phosphate receptor GPR6
Disease	N/A
Length	362
Amino acid sequence	MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEV
UniProt	P46095
Protein Data Bank	N/A
GPCR-HGmod model	P46095
3D structure model	This predicted structure model is from GPCR-EXP P46095.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3714130
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL7084453
Molecular formula	C11H10FN3OS2
IUPAC name	3-fluoro-N-(2-sulfanylideneimidazolidine-1-carbothioyl)benzamide
Molecular weight	283.339
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.7
Synonyms	CHEMBL3717378
Inchi Key	CQGZJRRRYFLKDR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H10FN3OS2/c12-8-3-1-2-7(6-8)9(16)14-11(18)15-5-4-13-10(15)17/h1-3,6H,4-5H2,(H,13,17)(H,14,16,18)
PubChem CID	9835479
ChEMBL	CHEMBL3717378
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	2620.0 nM	None	ChEMBL
IC50	3190.0 nM	None	ChEMBL

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