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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 6
Species	Homo sapiens (Human)
Gene	GPR6
Synonym	GPR6 Sphingosine 1-phosphate receptor GPR6
Disease	N/A
Length	362
Amino acid sequence	MNASAASLNDSQVVVVAAEGAAAAATAAGGPDTGEWGPPAAAALGAGGGANGSLELSSQLSAGPPGLLLPAVNPWDVLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVFQYLVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLCGCFQSKVPFRSRSPSEV
UniProt	P46095
Protein Data Bank	N/A
GPCR-HGmod model	P46095
3D structure model	This predicted structure model is from GPCR-EXP P46095.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3714130
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	AC1NC1KY
Molecular formula	C11H11N3OS2
IUPAC name	N-(2-sulfanylideneimidazolidine-1-carbothioyl)benzamide
Molecular weight	265.349
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.6
Synonyms	SCHEMBL7088439 1-(N-benzoylthiocarbamoyl)-2-imidazolidinethione CHEMBL3718086 N-(2-sulfanylideneimidazolidine-1-carbothioyl)benzamide
Inchi Key	CNUVXKFALYNKND-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H11N3OS2/c15-9(8-4-2-1-3-5-8)13-11(17)14-7-6-12-10(14)16/h1-5H,6-7H2,(H,12,16)(H,13,15,17)
PubChem CID	4526747
ChEMBL	CHEMBL3718086
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	100000.0 nM	None	ChEMBL

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