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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melatonin receptor type 1B
Species	Homo sapiens (Human)
Gene	MTNR1B
Synonym	MT2 receptor mel1b receptor Mel-1B-R
Disease	Epilepsy
Length	362
Amino acid sequence	MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
UniProt	P49286
Protein Data Bank	N/A
GPCR-HGmod model	P49286
3D structure model	This predicted structure model is from GPCR-EXP P49286.
BioLiP	N/A
Therapeutic Target Database	T48268
ChEMBL	CHEMBL1946
IUPHAR	288
DrugBank	BE0000327

Ligand

Name	CHEMBL3740377
Molecular formula	C32H32F4N2O4
IUPAC name	N-[2-[7-[4-[8-[2-[(2,2-difluoroacetyl)amino]ethyl]naphthalen-2-yl]oxybutoxy]naphthalen-1-yl]ethyl]-2,2-difluoroacetamide
Molecular weight	584.612
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	7.6
Synonyms	N/A
Inchi Key	ASNVLUVKCDAISR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H32F4N2O4/c33-29(34)31(39)37-15-13-23-7-3-5-21-9-11-25(19-27(21)23)41-17-1-2-18-42-26-12-10-22-6-4-8-24(28(22)20-26)14-16-38-32(40)30(35)36/h3-12,19-20,29-30H,1-2,13-18H2,(H,37,39)(H,38,40)
PubChem CID	127041170
ChEMBL	CHEMBL3740377
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	14.45 nM	MedChemComm, (2015) 6:7:1340	ChEMBL
Ki	15.0 nM	MedChemComm, (2015) 6:7:1340	ChEMBL

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